THE NEW SOCIAL WORKER's Books & More Shop: Books on Aging: Eye, Retina, and Visual System of the Mouse

Eye, Retina, and Visual System of the Mouse
enlarge	Creators: Leo M. Chalupa, Robert W. Williams Publisher: The MIT Press Category: Book List Price: ~~$135.00~~ Buy New: $109.92 as of 11/21/2009 04:40 PST details You Save: $25.08 (19%) New (22) Used (10) from $98.94 Seller: Amazon.com Media: Hardcover Edition: 1 Pages: 872 Number Of Items: 1 Shipping Weight (lbs): 4.3 Dimensions (in): 10.9 x 8.7 x 1.4 ISBN: 026203381X Dewey Decimal Number: 573.8819353 EAN: 9780262033817 ASIN: 026203381X Publication Date: August 31, 2008 Availability: Usually ships in 24 hours


Similar Items: Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods (Research Methods for Mutant Mice Series) The Retina: An Approachable Part of the Brain (Belknap Press) The First Steps in Seeing Fundamental Neuroscience, Third Edition (Squire,Fundamental Neuroscience) The Visual Neurosciences, 2 Volume Set, (Bradford Books)


Editorial Reviews: Product Description Recent years have seen a burst of studies on the mouse eye and visual system, fueled in large part by the relatively recent ability to produce mice with precisely defined changes in gene sequence. Mouse models have contributed to a wide range of scientific breakthroughs for a number of ocular and neurological diseases and have allowed researchers to address fundamental issues that were difficult to approach with other experimental models. This comprehensive guide to current research captures the first wave of studies in the field, with fifty-nine chapters by leading scholars that demonstrate the usefulness of mouse models as a bridge between experimental and clinical research. The opening chapters introduce the mouse as a species and research model, discussing such topics as the mouse's evolutionary history and the mammalian visual system. Subsequent sections explore more specialized subjects, considering optics, psychophysics, and the visual behaviors of mice; the organization of the adult mouse eye and central visual system; the development of the mouse eye (including comparisons to human development); the development and plasticity of retinal projections and visuotopic maps; mouse models for human eye disease (including glaucoma and cataracts); and the application of advanced genomic technologies (including gene therapy and genetic knockouts) to the mouse visual system. Readers of this reference will see that the study of mouse models has already demonstrated real translational prowess in vision research.

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